Assessment of the risk of developing cardiovascular disease in prediabetic and diabetic subjects with Insulinaemia
1 Department of Chemical Pathology, University of Port Harcourt Teaching Hospital, Choba, Port Harcourt, Nigeria.
2 Department of Biochemistry, University of Port Harcourt, Choba, Port Harcourt, Nigeria.
Research Article
World Journal of Advanced Engineering Technology and Sciences, 2022, 02(02), 048–055.
Article DOI: 10.53346/wjapls.2022.2.2.0023
Publication history:
Received on 13 March 2022; revised on 23 April 2022; accepted on 25 April 2022
Abstract:
Introduction: This examination investigated the risk of developing cardiovascular disease in pre-diabetic and diabetic subjects with insulinaemia. The assessment solidified the human diabetic subjects in the evaluation of the model and took the blood analytes to screen for diabetes.
Methodology: 120 male and female human subjects containing forty subjects each for control, pre-diabetics and diabetics facilitated for age, sex, height, weight, and BMI were enrolled into the assessment reliant upon decided measures. All of the three sets of human subjects were males and females independently. Every illustration of blood serum and plasma was explored using Randox and Accubind packs and an autoanalyser to test for various biochemical and hematological limits.
Results: The overall results revealed a colossal differentiation (p≤0.05) in the limits except for that of Na+. The 500mg/kg body weight part of the concentrate was ideal while there was a much basic development in the HOMA-IR with potential gains of 0.94±0.04, 2.28±0.17, and 3.25±0.44 for the three sets. The HOMA-IR is an alluring model, as compared to various models previously investigated. This assessment revealed that HOMA-IR works best in the management of diabetes in connection with various models.
Keywords:
Insulinaemia; Pre-Diabetic; Diabetic; Cardiovascular; Risk; Assessment
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