Contribution to the study of the antiparasitic activity of Euphorbia hirta macerate on rabbit coccidia

LANAN WASSY SOROMOU 1, MAMADOU FODÉ CAMARA 2, *, MAMADOU SIDIBE 2 and ALPHA IBRAHIMA DIALLO 2

1 Department of Applied Biology, University of Labé, 210 Labé, Republic of Guinea.
2 Department of Veterinary Medicine, Institute of Science and Veterinary Medicine, 09 Dalaba, Republic of Guinea.
 
Research Article
World Journal of Advanced Pharmaceutical and Life Sciences, 2023, 04(02), 022–026.
Article DOI: 10.53346/wjapls.2023.4.2.0066
Publication history: 
Received on 23 March 2023; revised on 04 May 2023; accepted on 07 May 2023
 
Abstract: 
The objective of this study was to evaluate the therapeutic properties of Euphorbia hirta macerate against coccidia, with a view to reducing the excessive use of antiparasitics in rabbit farms. The research methodology was based on the harvesting and treatment of the plant, the constitution of the different experimental batches, the identification of the infestation of the subjects, the determination of the parasite load of the different batches, the administration of the different anti-coccidial formulations, and the post-treatment laboratory analysis. In this experiment, 15 rabbits were used in 5 batches of 3. The product of interest was freshly macerated in drinking water at the concentration of 0.03 and administered per-os. The results showed that the macerate has dose-dependent anticoccidial activities. Weight gain was high in all subjects except the control lot.
 
Keywords: 
Euphorbia hirta; Antiparasitic activity; Coccidiosis; Digestive pathologies; Rabbit farming
 
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