COVID-induced pulmonary renal syndrome with severe intra-alveolar hemorrhage

Iza David Zabaneh *, Carla Edmonds MSN RN CNN and Kwabena Oppong Asafo-Agyei

TCU Burnett School of Medicine Fort Worth TX, Willis-knighton Health Care Shreveport LA, Christus Highland Hospital Shreveport LA, USA.
 
Research Article
World Journal of Advanced Pharmaceutical and Life Sciences, 2024, 06(02), 001–005​.
Article DOI: 10.53346/wjapls.2024.6.2.0029
 
Publication history: 
Received on 23 February 2024; revised on 05 April 2024; accepted on 08 April 2024
 
Abstract: 
Since the initial surge of COVID-19, there has been an increased number of connective tissue diseases and vasculitis associated with this diagnosis. These cases include systemic lupus erythematosus, lupus nephritis, antineutrophil cytoplasmic antibody (ANCA) associated vasculitis, polymyalgia, and giant cell arteritis. There are a number of presumed mechanisms behind that including the deregulation of the angiotensin-converting enzyme 2 as well as interferon related genes, leading to increased release of inflammation markers including cytokines as well as interleukin-6, complement activation and B cell proliferation and production of autoantibodies.

 

Keywords: 
COVID-19 infection; Respiratory Failure; Acute renal failure; Anti-Neutrophil cytoplasmic antibody
 
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