Long COVID: An unpredicted multisystem syndrome of COVID-19 disease
1 Associate Professor& Head, Pulmonary Medicine, MIMSR Medical college, & Venkatesh Hospital, Latur, Maharashtra, India
2 Junior Resident, Radiodiagnosis, MIMSR Medical college, Latur, Maharashtra, India
3 Associate Professor, Internal Medicine, MIMSR Medical college, Latur, Maharashtra, India
Review
World Journal of Advanced Pharmaceutical and Life Sciences, 2023, 04(01), 005–012.
Article DOI: 10.53346/wjapls.2023.4.1.0054
Publication history:
Received on 04 January 2023; revised on 18 February 2023; accepted on 21 February 2023
Abstract:
Long COVID is multisystem syndrome with nonspecific symptoms and organic signs of unidentified pathology occurs after COVID-19 disease. Long COVID symptoms has been documented in some cases irrespective of disease severity or hospitalization. Long COVID symptoms has significant impact on quality of life in those cases suffered from disease in recent past and lingering to almost two years since infection. Importantly, not all cases of COVID-19 were shown long COVID symptoms. Pathophysiology resulting into long COVID manifestations is still not completely validated. Researchers have reported ‘immune dysregulation’ and ‘coagulation abnormalities’ are probable pathophysiological mechanism for long COVID. Some of the long COVID effects shown complete reversibility including post COVID lung fibrosis. Reboot system to restore immune dysregulation and recovery in long COVID is real concern. Vaccination has not shown significant effect modifying long COVID manifestation.
Keywords:
Long COVID; COVID-19; Coagulation abnormalities; Immune dysregulation
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0