Pharmacogenomic approaches for tailoring medication to genetic profiles in diverse populations

Adeola Feyisitan Banji 1, Adeleke Damilola Adekola 2, * and Samuel Ajibola Dada 2

1 Independent Researcher, Lagos, Nigeria.
2 Syracuse University, NY, USA.
 
Review
World Journal of Advanced Pharmaceutical and Medical Research, 2024, 07(02), 109–118.
Article DOI: 10.53346/wjapmr.2024.7.2.0049
Publication history: 
Received on 07 October 2024; revised on 14 November 2024; accepted on 17 November 2024
 
Abstract: 
Pharmacogenomics, a branch of precision medicine, focuses on how genetic variations influence individual responses to drugs, allowing for more tailored and effective treatments. This approach has the potential to significantly enhance therapeutic outcomes by improving drug efficacy, minimizing adverse reactions, and optimizing medication use. By considering genetic makeup, pharmacogenomic strategies enable healthcare providers to personalize treatments for patients, particularly in the management of complex conditions like cancer, cardiovascular diseases, and mental health disorders. However, pharmacogenomics must be applied equitably across all populations to reach its full potential. Inclusive research and comprehensive policies are crucial in addressing disparities in access to pharmacogenomic testing and therapies, particularly for underrepresented and marginalized communities. This paper discusses the importance of advancing pharmacogenomic approaches in personalized medicine, emphasizing the need for diverse research and equitable access to ensure that these innovations benefit all patients.
 
Keywords: 
Pharmacogenomics; Precision medicine; Personalized treatment; Health equity; Genetic testing
 
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