Post covid lung fibrosis (PCLF) or post covid lung sequelae (PCLS) in treated case of severe COVID-19 Pneumonia case in Intensive care unit with ventilatory support and home oxygen therapy for twelve weeks
1 Associate Professor, Pulmonary Medicine, MIMSR Medical College, Venkatesh Hospital, Latur, Maharashtra, India.
2 Junior Resident, Radiodiagnosis, MIMSR Medical college, Latur, Maharashtra, India.
3 Professor, Radiodiagnosis, MIMSR Medical college, Latur, Maharashtra, India.
Case Study
World Journal of Advanced Pharmaceutical and Medical Research, 2023, 04(01), 030–041.
Article DOI: 10.53346/wjapmr.2023.4.1.0017
Publication history:
Received on 20 January 2023; revised on 28 February 2023; accepted on 01 March 2023
Abstract:
Lung fibrosis is final radiological outcome of COVID-19 pneumonia documented in proportionately majority of cases. Post COVID lung fibrosis is considered as worrisome radiological complication observed during early phase of pandemic. Time trends of final radiological outcome has evolved over months with or without treatment with antifibrotics and steroids. Importantly, Post covid lung fibrosis resolved more than fifty percent cases in six months and nearly in all cases after one year. In this case report we have documented PCLF in 32-year male hospitalized for severe COVID-19 illness with acute hypoxic respiratory failure secondary to ARDS (acute respiratory distress syndrome). He required high flow nasal canula oxygen supplementation with noninvasive ventilatory support for three weeks. He responded to medical treatment such as injection remdesivir, methylprednisolone and low molecular weight heparin injection. He was discharged to home with advice for home oxygen therapy and medicines such as steroids and antifibrotics Nintedanib. He required oxygen for twelve weeks. His chest imaging done at one year shown residual post covid sequel without any cardiopulmonary and exercise performance impact.
Keywords:
COVID-19; ARDS; Post covid lung fibrosis; Post covid sequelae; Remdesivir; Antifibrotics
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