Nypa fruticans endophytic fungus Cichorin A displays a weak cytotoxic activity against mouse lymphoma

Gideon Oyewole Alade * and Kola’ Kayode Ajibesin

Department of Pharmacognosy & Herbal Medicine, Niger Delta University, Wilberforce Island, Nigeria.
 
Research Article
World Journal of Advanced Pharmaceutical and Medical Research, 2023, 04(02), 008–011.
Article DOI: 10.53346/wjapmr.2023.4.2.0021
Publication history: 
Received on 26 February 2023; revised on 09 April 2023; accepted on 12 April 2023
 
Abstract: 
A keen interest and attention have been given to studies on Endophytic fungus as a substitute or an alternative to the traditional source of drugs which is principally plant as a result of its interesting bioactive products. This may be an additional means of increasing the yields of those already obtained from plants or a source of entirely new ones. In essence, it is a treasure trove of therapeutically active metabolites. The aim of the study was to challenge Cichorin A isolated from Pestalotiopsis sp. against mouse lymphoma cell line. The result showed that  it has a weak activity with a growth inhibitory effect of 31.2%
 
Keywords: 
Cichorin A; Fungus; Endophytic; Cytotoxic; Nypa fruticans
 
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