Medicinal plants with anti-plasmodial activity: A comprehensive review

Zahraa S Hadi 1, Baydaa Furhan Swadi 2, Ali Esmail Al-Snafi 3, * and MM Thuwaini 3

1 Department. of Biology, College of Education for women, University of AL- Shatrah, Iraq.
2 Department of Physiotherapy, College of Medical and Healthy Techniques, Southern Technique University, Basra, Iraq.
3 Department of Pharmacology, Faculty of Medicine, University of Thi Qar, Iraq.
 
Review
World Journal of Biological and Pharmaceutical Research, 2025, 08(02), 022-030.
Article DOI: 10.53346/wjbpr.2025.8.2.0017
Publication history: 
Received on 27 March 2025; revised on 06 May 2025; accepted on 09 May 2025
 
Abstract: 
Malaria is one of the life-threatening protozoal diseases in malaria-endemic regions of the world. It caused about 627,000 deaths in 2020. Recently, drug-resistant Plasmodium species was increased against all the available antimalarial drugs. Increased incidence of Plasmodium resistance necessitated continuous introducing of new drugs. Many drugs from natural sources showed potent antimalerial effects. In this review, Web of Science, Reseachgate, PubMed, Academia.edu, Google Scholar and Science Direct were searched for medicinal plants with anti malerial activity to encourage identification of the active ingredients, determination of clinical efficacy, investigation of the mode of action and safety.
 
Keywords: 
Medicinal plants; Herbs; Anti-plasmodial; Antimalerial; Pharmacology
 
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