Successful treatment of type II diabetes mellitus with infected diabetic foot ulcer caused by ESBL producing Klebsiella pneumonia with cefepime plus sulbactam (Supime): A case report

Vijay Shankar Upadhyay 1, * and Ayush Upadhayay 2

1 General Medicine, Ashadeep Hospital & Heart Care, Research Center, Jaunpur, Utter Pradesh, India.
2 PMCH Udaipur, Utter Pradesh, India.
 
Review
World Journal of Biological and Pharmaceutical Research, 2022, 02(02), 058–062.
Article DOI: 10.53346/wjbpr.2022.2.2.0024
Publication history: 
Received on 02 March 2022; revised on 04 April 2022; accepted on 06 April 2022
 
Abstract: 
Diabetic patients are at significant risk of developing neuropathy, leading to a diabetic foot injury. Complications of diabetic foot injury may lead to gangrene and non-traumatic lower extremity amputations. Diabetic patients with diabetic foot ulcers are more prone to bacterial infections and are associated with high chances of amputation. The diabetic patient flora provides an ideal environment for Gram-positive and Gram-negative bacterial growth, leading to increased morbidity and mortality. The antimicrobial-resistant Gram-negative bacterial infections in diabetic patients have a higher probability of amputation. Here we discuss a case of a 70-year male diabetic patient successfully treated with Supime (cefepime plus sulbactam) who had undergone an amputation of the right great toe and infected left foot ulcer due to ESBL producing K. Pneumonia.
 
Keywords: 
Diabetic Foot; ESBL; K Pneumonia; Supime; Cefepime plus sulbactam
 
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